A transcriptomic analysis of Echinococcus granulosus larval stages: implications for parasite biology and host adaptation.
Identifieur interne : 001292 ( Main/Exploration ); précédent : 001291; suivant : 001293A transcriptomic analysis of Echinococcus granulosus larval stages: implications for parasite biology and host adaptation.
Auteurs : John Parkinson [Canada] ; James D. Wasmuth ; Gustavo Salinas ; Cristiano V. Bizarro ; Chris Sanford ; Matthew Berriman ; Henrique B. Ferreira ; Arnaldo Zaha ; Mark L. Blaxter ; Rick M. Maizels ; Cecilia FernándezSource :
- PLoS neglected tropical diseases [ 1935-2735 ] ; 2012.
English descriptors
- KwdEn :
- MESH :
- genetics : Echinococcus granulosus, Larva.
- growth & development : Echinococcus granulosus, Larva.
- Animals, Expressed Sequence Tags, Molecular Sequence Data, Sequence Analysis, DNA, Transcriptome.
Abstract
The cestode Echinococcus granulosus--the agent of cystic echinococcosis, a zoonosis affecting humans and domestic animals worldwide--is an excellent model for the study of host-parasite cross-talk that interfaces with two mammalian hosts. To develop the molecular analysis of these interactions, we carried out an EST survey of E. granulosus larval stages. We report the salient features of this study with a focus on genes reflecting physiological adaptations of different parasite stages.
DOI: 10.1371/journal.pntd.0001897
PubMed: 23209850
Affiliations:
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Wasmuth</name></author><author><name sortKey="Salinas, Gustavo" sort="Salinas, Gustavo" uniqKey="Salinas G" first="Gustavo" last="Salinas">Gustavo Salinas</name></author><author><name sortKey="Bizarro, Cristiano V" sort="Bizarro, Cristiano V" uniqKey="Bizarro C" first="Cristiano V" last="Bizarro">Cristiano V. Bizarro</name></author><author><name sortKey="Sanford, Chris" sort="Sanford, Chris" uniqKey="Sanford C" first="Chris" last="Sanford">Chris Sanford</name></author><author><name sortKey="Berriman, Matthew" sort="Berriman, Matthew" uniqKey="Berriman M" first="Matthew" last="Berriman">Matthew Berriman</name></author><author><name sortKey="Ferreira, Henrique B" sort="Ferreira, Henrique B" uniqKey="Ferreira H" first="Henrique B" last="Ferreira">Henrique B. 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Wasmuth</name></author><author><name sortKey="Salinas, Gustavo" sort="Salinas, Gustavo" uniqKey="Salinas G" first="Gustavo" last="Salinas">Gustavo Salinas</name></author><author><name sortKey="Bizarro, Cristiano V" sort="Bizarro, Cristiano V" uniqKey="Bizarro C" first="Cristiano V" last="Bizarro">Cristiano V. Bizarro</name></author><author><name sortKey="Sanford, Chris" sort="Sanford, Chris" uniqKey="Sanford C" first="Chris" last="Sanford">Chris Sanford</name></author><author><name sortKey="Berriman, Matthew" sort="Berriman, Matthew" uniqKey="Berriman M" first="Matthew" last="Berriman">Matthew Berriman</name></author><author><name sortKey="Ferreira, Henrique B" sort="Ferreira, Henrique B" uniqKey="Ferreira H" first="Henrique B" last="Ferreira">Henrique B. 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To develop the molecular analysis of these interactions, we carried out an EST survey of E. granulosus larval stages. We report the salient features of this study with a focus on genes reflecting physiological adaptations of different parasite stages.</div></front></TEI><affiliations><list><country><li>Canada</li></country><region><li>Ontario</li></region><settlement><li>Toronto</li></settlement><orgName><li>Université de Toronto</li></orgName></list><tree><noCountry><name sortKey="Berriman, Matthew" sort="Berriman, Matthew" uniqKey="Berriman M" first="Matthew" last="Berriman">Matthew Berriman</name><name sortKey="Bizarro, Cristiano V" sort="Bizarro, Cristiano V" uniqKey="Bizarro C" first="Cristiano V" last="Bizarro">Cristiano V. Bizarro</name><name sortKey="Blaxter, Mark L" sort="Blaxter, Mark L" uniqKey="Blaxter M" first="Mark L" last="Blaxter">Mark L. 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